embryonic lethality during organogenesis, complete penetrance_Mapk8<tm1Flv>/Mapk8<tm1Flv>,Mapk9<tm1Flv>/Mapk9<tm1Flv>

http://metadb.riken.jp/0011098I129S1Sv129S2SvPasMapk8tm1FlvMapk8tm1FlvMapk9tm1FlvMapk9tm1FlvMapk8tm1FlvMapk9tm1Flv

embryonic lethality during organogenesis, complete penetrance_Mapk8<tm1Flv>/Mapk8<tm1Flv>,Mapk9<tm1Flv>/Mapk9<tm1Flv>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346862
• mitogen-activated protein kinase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346861

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk8<tm1Flv>/Mapk8<tm1Flv>,Mapk9<tm1Flv>/Mapk9<tm1Flv>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk8<tm1Flv>|Mapk9<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• C Y. Kuan, et.al., The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development., Neuron, 1999, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/10230788