embryonic lethality during organogenesis, complete penetrance_Psen1<tm1Pcw>/Psen1<tm1Pcw>,Psen2<tm1Ber>/Psen2<tm1Ber>

http://metadb.riken.jp/0011098I129S1Sv129S7SvEvBrd129X1SvJC57BL6JPsen1tm1PcwPsen1tm1PcwPsen2tm1BerPsen2tm1BerPsen1tm1PcwPsen2tm1Ber

embryonic lethality during organogenesis, complete penetrance_Psen1<tm1Pcw>/Psen1<tm1Pcw>,Psen2<tm1Ber>/Psen2<tm1Ber>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109284
• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm1Pcw>/Psen1<tm1Pcw>,Psen2<tm1Ber>/Psen2<tm1Ber>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<tm1Pcw>|Psen2<tm1Ber>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• D B. Donoviel, et.al., Mice lacking both presenilin genes exhibit early embryonic patterning defects., Genes & development, 1999, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10557208