embryonic lethality during organogenesis, complete penetrance_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm1Soff>/Gnaq<tm1Soff>

http://metadb.riken.jp/0011098I129S1Sv129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm1SoffGnaqtm1SoffGna11tm1SoffGnaqtm1Soff

embryonic lethality during organogenesis, complete penetrance_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm1Soff>/Gnaq<tm1Soff>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:95766
• guanine nucleotide binding protein, alpha q polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm1Soff>/Gnaq<tm1Soff>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna11<tm1Soff>|Gnaq<tm1Soff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• S. Offermanns, et.al., Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice., The EMBO journal, 1998, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/9687499