embryonic lethality during organogenesis, complete penetrance_Ext1<tm1Vcs>/Ext1<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

http://metadb.riken.jp/0011098I129S1Sv129X1SvJC57BL6Ext1tm1VcsExt1Hprttm1CAGcreMnnHprtExt1tm1VcsHprtExt1Hprttm1CAGcreMnn

embryonic lethality during organogenesis, complete penetrance_Ext1<tm1Vcs>/Ext1<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hypoxanthine guanine phosphoribosyl transferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96217
• exostoses (multiple) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:894663

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ext1<tm1Vcs>/Ext1<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ext1<tm1Vcs>|Hprt<+>|Ext1<+>|Hprt<tm1(CAG-cre)Mnn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Kevin B. Jones, et.al., A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080592