embryonic lethality during organogenesis, complete penetrance_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(CAG-cre)1Nagy/0,Tg(tetO-Vegfa)90Ala/0

http://metadb.riken.jp/0011098I129S1Sv129X1SvJFVBNICRGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgCAGcre1Nagy0TgtetOVegfa90Ala0GtROSA26Sortm1rtTAEGFPNagyTgCAGcre1NagyGtROSA26SorTgtetOVegfa90Ala

embryonic lethality during organogenesis, complete penetrance_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(CAG-cre)1Nagy/0,Tg(tetO-Vegfa)90Ala/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andras Nagy
  http://metadb.riken.jp/db/mgi_rdf/MGI:3586450
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 90, Ann L Akeson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3586337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(CAG-cre)1Nagy/0,Tg(tetO-Vegfa)90Ala/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>|Tg(CAG-cre)1Nagy|Gt(ROSA)26Sor<+>|Tg(tetO-Vegfa)90Ala

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Gusztav. Belteki, et.al., Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction., Nucleic acids research, 2005, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/15784609