embryonic lethality during organogenesis, complete penetrance_Npm1<Gt(VICTR37)704Lex>/Npm1<Gt(VICTR37)704Lex>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0011098I129S2SvPas129S5SvEvBrdC57BL6Npm1GtVICTR37704LexNpm1GtVICTR37704LexTrp53tm1TyjTrp53tm1TyjNpm1GtVICTR37704LexTrp53tm1Tyj

embryonic lethality during organogenesis, complete penetrance_Npm1<Gt(VICTR37)704Lex>/Npm1<Gt(VICTR37)704Lex>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nucleophosmin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:106184
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Npm1<Gt(VICTR37)704Lex>/Npm1<Gt(VICTR37)704Lex>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Npm1<Gt(VICTR37)704Lex>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Emanuela. Colombo, et.al., Nucleophosmin is required for DNA integrity and p19Arf protein stability., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16199867