embryonic lethality during organogenesis, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Tg(Pgk1-cre)1Lni/0

http://metadb.riken.jp/0011098I129S2SvPasBALBcC57BL6DBA2Phox2btm3JbrPhox2btm3JbrTgPgk1cre1Lni0Phox2btm3JbrTgPgk1cre1Lni

embryonic lethality during organogenesis, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Tg(Pgk1-cre)1Lni/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Peter Lonai
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178049
• paired-like homeobox 2b
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100882

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Tg(Pgk1-cre)1Lni/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Phox2b<tm3Jbr>|Tg(Pgk1-cre)1Lni

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Véronique. Dubreuil, et.al., Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19940179