embryonic lethality during organogenesis, complete penetrance_Mdm4<tm3.1Glo>/Mdm4<tm3.1Glo>

http://metadb.riken.jp/0011098I129S6SvEvTacC57BL6FVBNMdm4tm31GloMdm4tm31GloMdm4tm31Glo

embryonic lethality during organogenesis, complete penetrance_Mdm4<tm3.1Glo>/Mdm4<tm3.1Glo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107934

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm4<tm3.1Glo>/Mdm4<tm3.1Glo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm4<tm3.1Glo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Vinod. Pant, et.al., Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21730132