embryonic lethality during organogenesis, complete penetrance_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Abl2<tm1Ajk>/Abl2<tm1Ajk>

http://metadb.riken.jp/0011098I129SSvEv129S4SvJaeC57BL6JAbl1tm1MlgAbl1tm1MlgAbl2tm1AjkAbl2tm1AjkAbl2tm1AjkAbl1tm1Mlg

embryonic lethality during organogenesis, complete penetrance_Abl1<tm1Mlg>/Abl1<tm1Mlg>,Abl2<tm1Ajk>/Abl2<tm1Ajk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• c-abl oncogene 1, non-receptor tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:87859
• v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
  http://metadb.riken.jp/db/mgi_rdf/MGI:87860

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abl1<tm1Mlg>/Abl1<tm1Mlg>,Abl2<tm1Ajk>/Abl2<tm1Ajk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Abl2<tm1Ajk>|Abl1<tm1Mlg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• A J. Koleske, et.al., Essential roles for the Abl and Arg tyrosine kinases in neurulation., Neuron, 1998, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/9883720