lethality throughout fetal growth and development, complete penetrance_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Bmpr1b<tm1Kml>/Bmpr1b<tm1Kml>,Tg(Col2a1-cre)1Bhr/?

http://metadb.riken.jp/0011099I129SSvEv129S7SvEvBrdC57BL6SJLBmpr1atm21BhrBmpr1atm21BhrBmpr1btm1KmlBmpr1btm1KmlTgCol2a1cre1BhrTgCol2a1cre1BhrBmpr1btm1KmlBmpr1atm21Bhr

lethality throughout fetal growth and development, complete penetrance_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Bmpr1b<tm1Kml>/Bmpr1b<tm1Kml>,Tg(Col2a1-cre)1Bhr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• bone morphogenetic protein receptor, type 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338938
• bone morphogenetic protein receptor, type 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:107191
• transgene insertion 1, Richard R Behringer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Bmpr1b<tm1Kml>/Bmpr1b<tm1Kml>,Tg(Col2a1-cre)1Bhr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col2a1-cre)1Bhr|Bmpr1b<tm1Kml>|Bmpr1a<tm2.1Bhr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• Byeong S. Yoon, et.al., Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/15781876