lethality throughout fetal growth and development, complete penetrance_Spi1<tm1Sing>/Spi1<tm1Sing>

http://metadb.riken.jp/0011099I129SSvEvSpi1tm1SingSpi1tm1SingSpi1tm1Sing

lethality throughout fetal growth and development, complete penetrance_Spi1<tm1Sing>/Spi1<tm1Sing>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• spleen focus forming virus (SFFV) proviral integration oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98282

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Spi1<tm1Sing>/Spi1<tm1Sing>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Spi1<tm1Sing>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• E W. Scott, et.al., Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages., Science (New York, N.Y.), 1994, 265
  http://rdf.ncbi.nlm.nih.gov/pubmed/8079170
• M B. Kamath, et.al., Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity., Leukemia, 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/18354487