lethality throughout fetal growth and development, complete penetrance_Casp8<tm1.1Vmd>/Casp8<+>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

http://metadb.riken.jp/0011099IC57BL6NCasp8tm11VmdCasp8Ripk3tm2VmdRipk3tm2VmdCasp8tm11VmdCasp8Ripk3tm2Vmd

lethality throughout fetal growth and development, complete penetrance_Casp8<tm1.1Vmd>/Casp8<+>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• receptor-interacting serine-threonine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2154952
• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1.1Vmd>/Casp8<+>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp8<tm1.1Vmd>|Casp8<+>|Ripk3<tm2Vmd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• Kim. Newton, et.al., Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis., Science (New York, N.Y.), 2014, 343
  http://rdf.ncbi.nlm.nih.gov/pubmed/24557836