preweaning lethality, complete penetrance_Pak2<tm1Rjak>/Pak2<tm1Rjak>

http://metadb.riken.jp/0011100I129S1Sv129X1SvJC57BL6Pak2tm1RjakPak2tm1RjakPak2tm1Rjak

preweaning lethality, complete penetrance_Pak2<tm1Rjak>/Pak2<tm1Rjak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• p21 protein (Cdc42/Rac)-activated kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1339984

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pak2<tm1Rjak>/Pak2<tm1Rjak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pak2<tm1Rjak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete preweaning lethality
  http://purl.obolibrary.org/obo/MP_0011100

文献

http://purl.org/net/cito/citesAsAuthority

• Jerry W. Marlin, et.al., Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34., Mammalian genome : official journal of the International Mammalian Genome Society, 2011, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/21499899