preweaning lethality, complete penetrance_Erbb3<tm1.1Dwt>/Erbb3<tm2.1Dwt>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0011100I129S6SvEvTacC57BL6CBAErbb3tm11DwtErbb3tm21DwtTgSox2cre1Amc0Erbb3tm11DwtTgSox2cre1AmcErbb3tm21Dwt

preweaning lethality, complete penetrance_Erbb3<tm1.1Dwt>/Erbb3<tm2.1Dwt>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• erb-b2 receptor tyrosine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95411
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Erbb3<tm1.1Dwt>/Erbb3<tm2.1Dwt>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Erbb3<tm1.1Dwt>|Tg(Sox2-cre)1Amc|Erbb3<tm2.1Dwt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete preweaning lethality
  http://purl.obolibrary.org/obo/MP_0011100

文献

http://purl.org/net/cito/citesAsAuthority

• Daekee. Lee, et.al., Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19690388