prenatal lethality, incomplete penetrance_Porcn<tm1.1Vdv>/Porcn<+>,Tg(EIIa-cre)C5379Lmgd/0

http://metadb.riken.jp/0011101I129S4SvJaeSor129S5SvEvBrdC57BL6JFVBNPorcntm11VdvPorcnTgEIIacreC5379Lmgd0PorcnPorcntm11VdvTgEIIacreC5379Lmgd

prenatal lethality, incomplete penetrance_Porcn<tm1.1Vdv>/Porcn<+>,Tg(EIIa-cre)C5379Lmgd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• porcupine homolog (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890212
• transgene insertion C5379, Laboratory of Mammalian Genes and Development, Heiner Westphal
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Porcn<tm1.1Vdv>/Porcn<+>,Tg(EIIa-cre)C5379Lmgd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Porcn<+>|Porcn<tm1.1Vdv>|Tg(EIIa-cre)C5379Lmgd

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011101

文献

http://purl.org/net/cito/citesAsAuthority

• Wei. Liu, et.al., Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/22412863