prenatal lethality, incomplete penetrance_Idh1<tm3Mak>/Idh1<+>,Tg(Col2a1-cre)1Bhr/0

http://metadb.riken.jp/0011101IC57BL6SJLIdh1tm3MakIdh1TgCol2a1cre1Bhr0Idh1tm3MakIdh1TgCol2a1cre1Bhr

prenatal lethality, incomplete penetrance_Idh1<tm3Mak>/Idh1<+>,Tg(Col2a1-cre)1Bhr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• isocitrate dehydrogenase 1 (NADP+), soluble
  http://metadb.riken.jp/db/mgi_rdf/MGI:96413
• transgene insertion 1, Richard R Behringer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Idh1<tm3Mak>/Idh1<+>,Tg(Col2a1-cre)1Bhr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Idh1<tm3Mak>|Idh1<+>|Tg(Col2a1-cre)1Bhr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011101

文献

http://purl.org/net/cito/citesAsAuthority

• Makoto. Hirata, et.al., Mutant IDH is sufficient to initiate enchondromatosis in mice., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/25730874