embryonic lethality, incomplete penetrance_Optn<tm1.2Jda>/Optn<tm1.2Jda>

http://metadb.riken.jp/0011102I129S4SvJaeC57BL6JOptntm12JdaOptntm12JdaOptntm12Jda

embryonic lethality, incomplete penetrance_Optn<tm1.2Jda>/Optn<tm1.2Jda>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• optineurin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1918898

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Optn<tm1.2Jda>/Optn<tm1.2Jda>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Optn<tm1.2Jda>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011102

文献

http://purl.org/net/cito/citesAsAuthority

• Ivana. Munitic, et.al., Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells., Journal of immunology (Baltimore, Md. : 1950), 2013, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/24244017