embryonic lethality, incomplete penetrance_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Rspo1<tm1Mcch>/Rspo1<tm1Mcch>,Tg(Nr5a1-cre)5Asc/?

http://metadb.riken.jp/0011102I129SvC57BL6CBACtnnb1tm1MmtCtnnb1Rspo1tm1McchRspo1tm1McchTgNr5a1cre5AscCtnnb1Ctnnb1tm1MmtTgNr5a1cre5AscRspo1tm1Mcch

embryonic lethality, incomplete penetrance_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Rspo1<tm1Mcch>/Rspo1<tm1Mcch>,Tg(Nr5a1-cre)5Asc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andreas Schedl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3041880
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• R-spondin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183426

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Mmt>/Ctnnb1<+>,Rspo1<tm1Mcch>/Rspo1<tm1Mcch>,Tg(Nr5a1-cre)5Asc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<+>|Ctnnb1<tm1Mmt>|Tg(Nr5a1-cre)5Asc|Rspo1<tm1Mcch>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011102

文献

http://purl.org/net/cito/citesAsAuthority

• Anne-Amandine. Chassot, et.al., Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary., Human molecular genetics, 2008, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/18250098