embryonic lethality during organogenesis, incomplete penetrance_Dyrk1a<tm1Mla>/Dyrk1a<tm1Mla>

http://metadb.riken.jp/0011108I129P2OlaHsdC57BL6Dyrk1atm1MlaDyrk1atm1MlaDyrk1atm1Mla

embryonic lethality during organogenesis, incomplete penetrance_Dyrk1a<tm1Mla>/Dyrk1a<tm1Mla>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1330299

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dyrk1a<tm1Mla>/Dyrk1a<tm1Mla>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dyrk1a<tm1Mla>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• Vassiliki. Fotaki, et.al., Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12192061