embryonic lethality during organogenesis, incomplete penetrance_Rbbp6<tm1Xya>/Rbbp6<tm1Xya>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0011108I129S6SvEvTac129S7SvEvBrdRbbp6tm1XyaRbbp6tm1XyaTrp53tm1BrdTrp53tm1BrdRbbp6tm1XyaTrp53tm1Brd

embryonic lethality during organogenesis, incomplete penetrance_Rbbp6<tm1Xya>/Rbbp6<tm1Xya>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• retinoblastoma binding protein 6, ubiquitin ligase
  http://metadb.riken.jp/db/mgi_rdf/MGI:894835

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rbbp6<tm1Xya>/Rbbp6<tm1Xya>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rbbp6<tm1Xya>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• Li. Li, et.al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17470788