embryonic lethality during organogenesis, incomplete penetrance_Porcn<tm1.1Vdv>/Porcn<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

http://metadb.riken.jp/0011108I129SSvC57BL6JPorcntm11VdvPorcnHprttm1CAGcreMnnHprtPorcnPorcntm11VdvHprttm1CAGcreMnnHprt

embryonic lethality during organogenesis, incomplete penetrance_Porcn<tm1.1Vdv>/Porcn<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• porcupine homolog (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890212
• hypoxanthine guanine phosphoribosyl transferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96217

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Porcn<tm1.1Vdv>/Porcn<+>,Hprt<tm1(CAG-cre)Mnn>/Hprt<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Porcn<+>|Porcn<tm1.1Vdv>|Hprt<tm1(CAG-cre)Mnn>|Hprt<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• Wei. Liu, et.al., Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/22412863