embryonic lethality during organogenesis, incomplete penetrance_Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0011108IC3HC57BL6FVBNTgCAGcatPtpn11Q97R1Rbns0TgTekcre12Flv0TgCAGcatPtpn11Q97R1RbnsTgTekcre12Flv

embryonic lethality during organogenesis, incomplete penetrance_Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey Robbins
  http://metadb.riken.jp/db/mgi_rdf/MGI:3822047
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cat,-Ptpn11*Q97R)1Rbns|Tg(Tek-cre)12Flv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• Maike. Krenz, et.al., Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19017799