lethality throughout fetal growth and development, incomplete penetrance_Ppp2ca<tm1.1Nju>/Ppp2ca<tm1.1Nju>,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0011109I129S6SvEvTacC57BL6Ppp2catm11NjuPpp2catm11NjuTgTekcre12Flv0TgTekcre12FlvPpp2catm11Nju

lethality throughout fetal growth and development, incomplete penetrance_Ppp2ca<tm1.1Nju>/Ppp2ca<tm1.1Nju>,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  http://metadb.riken.jp/db/mgi_rdf/MGI:1321159
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ppp2ca<tm1.1Nju>/Ppp2ca<tm1.1Nju>,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)12Flv|Ppp2ca<tm1.1Nju>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011109

文献

http://purl.org/net/cito/citesAsAuthority

• Weiqian. Chen, et.al., Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21514445