preweaning lethality, incomplete penetrance_Wrn<tm1Led>/Wrn<tm1Led>

http://metadb.riken.jp/0011110EI129S6SvEvTacorI129S6SvEvTacNIHBlackSwissWrntm1LedWrntm1LedWrntm1Led

preweaning lethality, incomplete penetrance_Wrn<tm1Led>/Wrn<tm1Led>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Werner syndrome RecQ like helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109635

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Wrn<tm1Led>/Wrn<tm1Led>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Wrn<tm1Led>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial preweaning lethality
  http://purl.obolibrary.org/obo/MP_0011110

文献

http://purl.org/net/cito/citesAsAuthority

• M. Lebel, et.al., A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/9789047