preweaning lethality, incomplete penetrance_Tg(Camk2a-tTA)1Mmay/0,Tg(PDGFB-APPSwInd)20Lms/0,Tg(tetO-MAPT*A152T)L1Lms/0

http://metadb.riken.jp/0011110IC57BL6C57BL6JDBA2TgCamk2atTA1Mmay0TgPDGFBAPPSwInd20Lms0TgtetOMAPTA152TL1Lms0TgtetOMAPTA152TL1LmsTgPDGFBAPPSwInd20LmsTgCamk2atTA1Mmay

preweaning lethality, incomplete penetrance_Tg(Camk2a-tTA)1Mmay/0,Tg(PDGFB-APPSwInd)20Lms/0,Tg(tetO-MAPT*A152T)L1Lms/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 20, Lennart Mucke
  http://metadb.riken.jp/db/mgi_rdf/MGI:3057146
• transgene insertion L1, Lennart Mucke
  http://metadb.riken.jp/db/mgi_rdf/MGI:5788164
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(PDGFB-APPSwInd)20Lms/0,Tg(tetO-MAPT*A152T)L1Lms/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-MAPT*A152T)L1Lms|Tg(PDGFB-APPSwInd)20Lms|Tg(Camk2a-tTA)1Mmay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial preweaning lethality
  http://purl.obolibrary.org/obo/MP_0011110

文献

http://purl.org/net/cito/citesAsAuthority

• Sumihiro. Maeda, et.al., Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice., EMBO reports, 2016, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/26931567