decreased excitatory postsynaptic current amplitude_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm1c(EUCOMM)Wtsi>,Tg(Slc6a4-cre)ET127Gsat/0

http://metadb.riken.jp/0011270IC57BL6C57BL6NFVBNSJLGrin1tm1cEUCOMMWtsiGrin1tm1cEUCOMMWtsiTgSlc6a4creET127Gsat0TgSlc6a4creET127GsatGrin1tm1cEUCOMMWtsi

decreased excitatory postsynaptic current amplitude_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm1c(EUCOMM)Wtsi>,Tg(Slc6a4-cre)ET127Gsat/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819
• transgene insertion ET127, GENSAT Project at Rockefeller University
  http://metadb.riken.jp/db/mgi_rdf/MGI:4367072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm1c(EUCOMM)Wtsi>,Tg(Slc6a4-cre)ET127Gsat/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Slc6a4-cre)ET127Gsat|Grin1<tm1c(EUCOMM)Wtsi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased excitatory postsynaptic current amplitude
  http://purl.obolibrary.org/obo/MP_0011270

文献

http://purl.org/net/cito/citesAsAuthority

• Zhong-wei. Zhang, et.al., Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23277569