abnormal renal glomerulus basement membrane morphology_Agrn<tm1Rwb>/Agrn<tm1Rwb>,Tg(NPHS2-cre)295Lbh/0

http://metadb.riken.jp/0011348I129S1Sv129X1SvJC57BL6Agrntm1RwbAgrntm1RwbTgNPHS2cre295Lbh0Agrntm1RwbTgNPHS2cre295Lbh

abnormal renal glomerulus basement membrane morphology_Agrn<tm1Rwb>/Agrn<tm1Rwb>,Tg(NPHS2-cre)295Lbh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 295, Lawrence B Holzman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450360
• agrin
  http://metadb.riken.jp/db/mgi_rdf/MGI:87961

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Agrn<tm1Rwb>/Agrn<tm1Rwb>,Tg(NPHS2-cre)295Lbh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Agrn<tm1Rwb>|Tg(NPHS2-cre)295Lbh

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal glomerulus basement membrane morphology
  http://purl.obolibrary.org/obo/MP_0011348

文献

http://purl.org/net/cito/citesAsAuthority

• Scott J. Harvey, et.al., Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity., The American journal of pathology, 2007, 171
  http://rdf.ncbi.nlm.nih.gov/pubmed/17591961