decreased kidney apoptosis_Ctdnep1<tm3Ryn>/Ctdnep1<tm3Ryn>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

http://metadb.riken.jp/0011371I129X1SvJC57BL6C57BL6JCtdnep1tm3RynCtdnep1tm3RynGtROSA26Sortm1EYFPCosGtROSA26SorSix2tm1tTAtetOEGFPcreAmcSix2Six2tm1tTAtetOEGFPcreAmcSix2GtROSA26Sortm1EYFPCosCtdnep1tm3RynGtROSA26Sor

decreased kidney apoptosis_Ctdnep1<tm3Ryn>/Ctdnep1<tm3Ryn>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• CTD nuclear envelope phosphatase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914431
• sine oculis-related homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102778

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctdnep1<tm3Ryn>/Ctdnep1<tm3Ryn>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Six2<tm1(tTA,tetO-EGFP/cre)Amc>|Six2<+>|Gt(ROSA)26Sor<tm1(EYFP)Cos>|Ctdnep1<tm3Ryn>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased kidney apoptosis
  http://purl.obolibrary.org/obo/MP_0011371

文献

http://purl.org/net/cito/citesAsAuthority

• Masaji. Sakaguchi, et.al., The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth., Nature communications, 2013, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/23360989