increased metanephric mesenchyme apoptosis_Fgfr1<tm1Jpa>/Fgfr1<tm1Jpa>,Fgfr2<tm3.1Lni>/Fgfr2<tm3.1Lni>,Tg(Pax3-cre)1Joe/0

http://metadb.riken.jp/0011386I129SvBALBcC57BL6FVBNSJLFgfr1tm1JpaFgfr1tm1JpaFgfr2tm31LniFgfr2tm31LniTgPax3cre1Joe0Fgfr1tm1JpaFgfr2tm31LniTgPax3cre1Joe

increased metanephric mesenchyme apoptosis_Fgfr1<tm1Jpa>/Fgfr1<tm1Jpa>,Fgfr2<tm3.1Lni>/Fgfr2<tm3.1Lni>,Tg(Pax3-cre)1Joe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95523
• fibroblast growth factor receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95522
• transgene insertion 1, Jonathan A Epstein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176201

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgfr1<tm1Jpa>/Fgfr1<tm1Jpa>,Fgfr2<tm3.1Lni>/Fgfr2<tm3.1Lni>,Tg(Pax3-cre)1Joe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgfr1<tm1Jpa>|Fgfr2<tm3.1Lni>|Tg(Pax3-cre)1Joe

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metanephric mesenchyme apoptosis
  http://purl.obolibrary.org/obo/MP_0011386

文献

http://purl.org/net/cito/citesAsAuthority

• Sunder. Sims-Lucas, et.al., Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21128305