lethality, complete penetrance_Nr3c1<tm1.1Mvc>/Nr3c1<tm1.1Mvc>,Tg(Sim1-cre)1Lowl/0

http://metadb.riken.jp/0011400I129C57BL6FVBNr3c1tm11MvcNr3c1tm11MvcTgSim1cre1Lowl0Nr3c1tm11MvcTgSim1cre1Lowl

lethality, complete penetrance_Nr3c1<tm1.1Mvc>/Nr3c1<tm1.1Mvc>,Tg(Sim1-cre)1Lowl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3692524
• nuclear receptor subfamily 3, group C, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95824

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nr3c1<tm1.1Mvc>/Nr3c1<tm1.1Mvc>,Tg(Sim1-cre)1Lowl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nr3c1<tm1.1Mvc>|Tg(Sim1-cre)1Lowl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality
  http://purl.obolibrary.org/obo/MP_0011400

文献

http://purl.org/net/cito/citesAsAuthority

• Freddy D. Jeanneteau, et.al., BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22232675