increased renal glomerulus basement membrane thickness_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Mmp9<tm1Tvu>/Mmp9<tm1Tvu>

http://metadb.riken.jp/0011409I129S1Sv129S6SvEvTac129X1SvJCol4a3tm1JhmCol4a3tm1JhmMmp9tm1TvuMmp9tm1TvuCol4a3tm1JhmMmp9tm1Tvu

increased renal glomerulus basement membrane thickness_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Mmp9<tm1Tvu>/Mmp9<tm1Tvu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type IV, alpha 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:104688
• matrix metallopeptidase 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:97011

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Mmp9<tm1Tvu>/Mmp9<tm1Tvu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col4a3<tm1Jhm>|Mmp9<tm1Tvu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased renal glomerulus basement membrane thickness
  http://purl.obolibrary.org/obo/MP_0011409

文献

http://purl.org/net/cito/citesAsAuthority

• K L. Andrews, et.al., Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome., The American journal of pathology, 2000, 157
  http://rdf.ncbi.nlm.nih.gov/pubmed/10880400