decreased dopaminergic neuron number_En1<tm2Alj>/En1<+>,Tg(Th-EGFP)6-7Okn/?

http://metadb.riken.jp/0011448I129S1Sv129X1SvJC57BL6DBA2JOF1En1tm2AljEn1TgThEGFP67OknTgThEGFP67OknEn1tm2AljEn1

decreased dopaminergic neuron number_En1<tm2Alj>/En1<+>,Tg(Th-EGFP)6-7Okn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6-7, Hideyuki Okano
  http://metadb.riken.jp/db/mgi_rdf/MGI:5604270
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm2Alj>/En1<+>,Tg(Th-EGFP)6-7Okn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Th-EGFP)6-7Okn|En1<tm2Alj>|En1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopaminergic neuron number
  http://purl.obolibrary.org/obo/MP_0011448

文献

http://purl.org/net/cito/citesAsAuthority

• Ulrika. Nordströma, et.al., Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease., Neurobiology of disease, 2015, 73
  http://rdf.ncbi.nlm.nih.gov/pubmed/25281317