increased urination frequency_Kcnma1<tm1Ruth>/Kcnma1<tm2.1Ruth>,X/Tg(Myh11-cre/ERT2)1Soff

http://metadb.riken.jp/0011535I129SvC57BL6FVBNKcnma1tm1RuthKcnma1tm21RuthXTgMyh11creERT21SoffKcnma1tm1RuthKcnma1tm21RuthTgMyh11creERT21Soff

increased urination frequency_Kcnma1<tm1Ruth>/Kcnma1<tm2.1Ruth>,X/Tg(Myh11-cre/ERT2)1Soff

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268
• potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kcnma1<tm1Ruth>/Kcnma1<tm2.1Ruth>,X/Tg(Myh11-cre/ERT2)1Soff

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kcnma1<tm1Ruth>|Kcnma1<tm2.1Ruth>|Tg(Myh11-cre/ERT2)1Soff

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased urination frequency
  http://purl.obolibrary.org/obo/MP_0011535

文献

http://purl.org/net/cito/citesAsAuthority

• Franz. Sprossmann, et.al., Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder., The FEBS journal, 2009, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/19220851