increased phosphatidylcholine-sterol O-acyltransferase activity_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat2<tm1Far>/Soat2<tm1Far>

http://metadb.riken.jp/0011599I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat2tm1FarSoat2tm1FarApoetm1UncSoat2tm1Far

increased phosphatidylcholine-sterol O-acyltransferase activity_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat2<tm1Far>/Soat2<tm1Far>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sterol O-acyltransferase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1332226
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Soat2<tm1Far>/Soat2<tm1Far>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apoe<tm1Unc>|Soat2<tm1Far>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased phosphatidylcholine-sterol O-acyltransferase activity
  http://purl.obolibrary.org/obo/MP_0011599

文献

http://purl.org/net/cito/citesAsAuthority

• Emily L. Willner, et.al., Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12538880