increased fibroblast proliferation_Cav1<tm1Mls>/Cav1<tm1Mls>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>

http://metadb.riken.jp/0011703I129SvC57BL6SJLCav1tm1MlsCav1tm1MlsCdkn2atm1RdpCdkn2atm1RdpCav1tm1MlsCdkn2atm1Rdp

increased fibroblast proliferation_Cav1<tm1Mls>/Cav1<tm1Mls>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caveolin 1, caveolae protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:102709
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cav1<tm1Mls>/Cav1<tm1Mls>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cav1<tm1Mls>|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fibroblast proliferation
  http://purl.obolibrary.org/obo/MP_0011703

文献

http://purl.org/net/cito/citesAsAuthority

• Terence M. Williams, et.al., Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15044451