increased pancreatic beta cell proliferation_Atf4<tm1Tow>/Atf4<+>,Ptprv<tm1Asmi>/Ptprv<+>

http://metadb.riken.jp/0011819EI129P2OlaHsd129S1Sv129X1SvJC57BL6JNIHBlackSwissorI129P2OlaHsdC57BL6JNIHBlackSwissAtf4tm1TowAtf4Ptprvtm1AsmiPtprvPtprvAtf4Atf4tm1TowPtprvtm1Asmi

increased pancreatic beta cell proliferation_Atf4<tm1Tow>/Atf4<+>,Ptprv<tm1Asmi>/Ptprv<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activating transcription factor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88096
• protein tyrosine phosphatase, receptor type, V
  http://metadb.riken.jp/db/mgi_rdf/MGI:108027

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atf4<tm1Tow>/Atf4<+>,Ptprv<tm1Asmi>/Ptprv<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptprv<+>|Atf4<+>|Atf4<tm1Tow>|Ptprv<tm1Asmi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J * NIH Black Swiss) or (involves: 129P2/OlaHsd * C57BL/6J * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell proliferation
  http://purl.obolibrary.org/obo/MP_0011819

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsuya. Yoshizawa, et.al., The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19726872