decreased pancreatic beta cell proliferation_Ghr<tm1.1Dlr>/Ghr<tm1.1Dlr>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0011820I129S4SvJaeC3HC57BL6DBAGhrtm11DlrGhrtm11DlrTgIns2cre25Mgn0Ghrtm11DlrTgIns2cre25Mgn

decreased pancreatic beta cell proliferation_Ghr<tm1.1Dlr>/Ghr<tm1.1Dlr>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth hormone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95708
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ghr<tm1.1Dlr>/Ghr<tm1.1Dlr>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ghr<tm1.1Dlr>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C3H * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell proliferation
  http://purl.obolibrary.org/obo/MP_0011820

文献

http://purl.org/net/cito/citesAsAuthority

• Yingjie. Wu, et.al., Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21555853