increased hematopoietic stem cell proliferation_Tgfbr1<tm1.1Karl>/Tgfbr1<tm1.1Karl>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0011902I129C57BL6CBATgfbr1tm11KarlTgfbr1tm11KarlTgMx1cre1Cgn0TgMx1cre1CgnTgfbr1tm11Karl

increased hematopoietic stem cell proliferation_Tgfbr1<tm1.1Karl>/Tgfbr1<tm1.1Karl>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor I
  http://metadb.riken.jp/db/mgi_rdf/MGI:98728
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tgfbr1<tm1.1Karl>/Tgfbr1<tm1.1Karl>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Tgfbr1<tm1.1Karl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell proliferation
  http://purl.obolibrary.org/obo/MP_0011902

文献

http://purl.org/net/cito/citesAsAuthority

• Jonas. Larsson, et.al., TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro., Blood, 2003, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/12842983