decreased susceptibility to hypertension_Rock2<tm1.1Itl>/Rock2<+>,Tg(Tagln-cre)1Her/0

http://metadb.riken.jp/0012046B6CgRock2tm11ItlTgTaglncre1HerRock2tm11ItlRock2TgTaglncre1Her0TgTaglncre1HerRock2tm11ItlRock2

decreased susceptibility to hypertension_Rock2<tm1.1Itl>/Rock2<+>,Tg(Tagln-cre)1Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450259
• Rho-associated coiled-coil containing protein kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:107926

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rock2<tm1.1Itl>/Rock2<+>,Tg(Tagln-cre)1Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tagln-cre)1Her|Rock2<tm1.1Itl>|Rock2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Rock2<tm1.1Itl> Tg(Tagln-cre)1Her

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to hypertension
  http://purl.obolibrary.org/obo/MP_0012046

文献

http://purl.org/net/cito/citesAsAuthority

• Toru. Shimizu, et.al., Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice., Arteriosclerosis, thrombosis, and vascular biology, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/24135024