midface hypoplasia_Fgfr2<tm2Cxd>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0

http://metadb.riken.jp/0012085I129S6SvEvTacC57BL6JFVBNFgfr2tm2CxdFgfr2TgEIIacreC5379Lmgd0TgEIIacreC5379LmgdFgfr2Fgfr2tm2Cxd

midface hypoplasia_Fgfr2<tm2Cxd>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95523
• transgene insertion C5379, Laboratory of Mammalian Genes and Development, Heiner Westphal
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgfr2<tm2Cxd>/Fgfr2<+>,Tg(EIIa-cre)C5379Lmgd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(EIIa-cre)C5379Lmgd|Fgfr2<+>|Fgfr2<tm2Cxd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• midface hypoplasia
  http://purl.obolibrary.org/obo/MP_0012085

文献

http://purl.org/net/cito/citesAsAuthority

• Roopa. Purushothaman, et.al., Facial suture synostosis of newborn Fgfr1(P250R/+) and Fgfr2(S252W/+) mouse models of Pfeiffer and Apert syndromes., Birth defects research. Part A, Clinical and molecular teratology, 2011, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/21538817