decreased endothelial cell proliferation_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Pfkfb3<tm1Pec>/Pfkfb3<tm1Pec>,Tg(Cdh5-cre/ERT2)1Rha/0

http://metadb.riken.jp/0012201I129S1Sv129X1SvJGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorPfkfb3tm1PecPfkfb3tm1PecTgCdh5creERT21Rha0TgCdh5creERT21RhaPfkfb3tm1PecGtROSA26SorGtROSA26Sortm4ACTBtdTomatoEGFPLuo

decreased endothelial cell proliferation_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Pfkfb3<tm1Pec>/Pfkfb3<tm1Pec>,Tg(Cdh5-cre/ERT2)1Rha/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181202
• transgene insertion 1, Ralf H Adams
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848980

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Pfkfb3<tm1Pec>/Pfkfb3<tm1Pec>,Tg(Cdh5-cre/ERT2)1Rha/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cdh5-cre/ERT2)1Rha|Pfkfb3<tm1Pec>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased endothelial cell proliferation
  http://purl.obolibrary.org/obo/MP_0012201

文献

http://purl.org/net/cito/citesAsAuthority

• Katrien. De Bock, et.al., Role of PFKFB3-driven glycolysis in vessel sprouting., Cell, 2013, 154
  http://rdf.ncbi.nlm.nih.gov/pubmed/23911327