decreased susceptibility to induction of seizure by inducing agent_Adk<tm2Bois>/Adk<tm2Bois>,Adora2a<tm1Jfc>/Adora2a<tm1Jfc>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0012348I129S4SvJaeC57BL6SJLAdktm2BoisAdktm2BoisAdora2atm1JfcAdora2atm1JfcTgNescre1Kln0Adora2atm1JfcTgNescre1KlnAdktm2Bois

decreased susceptibility to induction of seizure by inducing agent_Adk<tm2Bois>/Adk<tm2Bois>,Adora2a<tm1Jfc>/Adora2a<tm1Jfc>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenosine A2a receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99402
• adenosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:87930
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adk<tm2Bois>/Adk<tm2Bois>,Adora2a<tm1Jfc>/Adora2a<tm1Jfc>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adora2a<tm1Jfc>|Tg(Nes-cre)1Kln|Adk<tm2Bois>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to induction of seizure by inducing agent
  http://purl.obolibrary.org/obo/MP_0012348

文献

http://purl.org/net/cito/citesAsAuthority

• Ursula S. Sandau, et.al., Adenosine Kinase Deficiency in the Brain Results in Maladaptive Synaptic Plasticity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/27903722