increased lymphoma incidence_Irf1<tm1Mak>/Irf1<tm1Mak>,Trp53<tm1Sia>/Trp53<tm1Sia>

http://metadb.riken.jp/0012431I129S2SvPasC57BL6CBAIrf1tm1MakIrf1tm1MakTrp53tm1SiaTrp53tm1SiaTrp53tm1SiaIrf1tm1Mak

increased lymphoma incidence_Irf1<tm1Mak>/Irf1<tm1Mak>,Trp53<tm1Sia>/Trp53<tm1Sia>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interferon regulatory factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96590
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irf1<tm1Mak>/Irf1<tm1Mak>,Trp53<tm1Sia>/Trp53<tm1Sia>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Sia>|Irf1<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• H. Nozawa, et.al., Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53., Genes & development, 1999, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10346812