increased lymphoma incidence_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Lck-cre)1Cwi/?

http://metadb.riken.jp/0012431I129S2SvPasC57BL6Fbxw7tm1KeiFbxw7tm1KeiTrp53tm1TyjTrp53tm1TyjTgLckcre1CwiFbxw7tm1KeiTrp53tm1TyjTgLckcre1Cwi

increased lymphoma incidence_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Lck-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687
• F-box and WD-40 domain protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354695

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Lck-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fbxw7<tm1Kei>|Trp53<tm1Tyj>|Tg(Lck-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• Ichiro. Onoyama, et.al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17984302