increased lymphoma incidence_Trp53<tm3Tyj>/Trp53<+>,Tg(KRT14-cre)8Brn/?

http://metadb.riken.jp/0012431I129S4SvJaeFVBNSKH1Trp53tm3TyjTrp53TgKRT14cre8BrnTgKRT14cre8BrnTrp53Trp53tm3Tyj

increased lymphoma incidence_Trp53<tm3Tyj>/Trp53<+>,Tg(KRT14-cre)8Brn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm3Tyj>/Trp53<+>,Tg(KRT14-cre)8Brn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-cre)8Brn|Trp53<+>|Trp53<tm3Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * FVB/N * SKH1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• Susan W P. Wijnhoven, et.al., Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17510390