decreased intestinal adenoma incidence_Bmi1<tm1.1Lees>/Bmi1<tm1.1Lees>,Apc<tm2Cip>/Apc<+>,Tg(Vil-cre)20Syr/0

http://metadb.riken.jp/0012434I129P2OlaHsd129S4SvJaeC57BL6DBA2Bmi1tm11LeesBmi1tm11LeesApctm2CipApcTgVilcre20Syr0Apctm2CipApcBmi1tm11LeesTgVilcre20Syr

decreased intestinal adenoma incidence_Bmi1<tm1.1Lees>/Bmi1<tm1.1Lees>,Apc<tm2Cip>/Apc<+>,Tg(Vil-cre)20Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Bmi1 polycomb ring finger oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88174
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• transgene insertion 20, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053809

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmi1<tm1.1Lees>/Bmi1<tm1.1Lees>,Apc<tm2Cip>/Apc<+>,Tg(Vil-cre)20Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm2Cip>|Apc<+>|Bmi1<tm1.1Lees>|Tg(Vil-cre)20Syr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased intestinal adenoma incidence
  http://purl.obolibrary.org/obo/MP_0012434

文献

http://purl.org/net/cito/citesAsAuthority

• M A. Maynard, et.al., Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer., Oncogene, 2014, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23955081