decreased mammary gland tumor incidence in breeding females_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Cxcr4<tm2Yzo>/Cxcr4<tm2Yzo>,Tg(Wap-cre)11738Mam/0,Tg(Wap-Hgf)402Mig/0

http://metadb.riken.jp/0012568FVBCgCxcr4tm2YzoCtnnb1tm1MmtTgWapcre11738MamTgWapHgf402MigCtnnb1tm1MmtCtnnb1Cxcr4tm2YzoCxcr4tm2YzoTgWapcre11738Mam0TgWapHgf402Mig0TgWapHgf402MigCxcr4tm2YzoCtnnb1tm1MmtCtnnb1TgWapcre11738Mam

decreased mammary gland tumor incidence in breeding females_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Cxcr4<tm2Yzo>/Cxcr4<tm2Yzo>,Tg(Wap-cre)11738Mam/0,Tg(Wap-Hgf)402Mig/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-X-C motif) receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:109563
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• transgene insertion 402, Marta I Gallego
  http://metadb.riken.jp/db/mgi_rdf/MGI:3037894
• transgene insertion 11738, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176164

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Mmt>/Ctnnb1<+>,Cxcr4<tm2Yzo>/Cxcr4<tm2Yzo>,Tg(Wap-cre)11738Mam/0,Tg(Wap-Hgf)402Mig/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wap-Hgf)402Mig|Cxcr4<tm2Yzo>|Ctnnb1<tm1Mmt>|Ctnnb1<+>|Tg(Wap-cre)11738Mam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.Cg-Cxcr4<tm2Yzo> Ctnnb1<tm1Mmt> Tg(Wap-cre)11738Mam Tg(Wap-Hgf)402Mig

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mammary gland tumor incidence in breeding females
  http://purl.obolibrary.org/obo/MP_0012568

文献

http://purl.org/net/cito/citesAsAuthority

• Jane D. Holland, et.al., Combined Wnt/β-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome., Cell reports, 2013, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/24290754