abnormal enteric neural crest cell migration_Gata4<tm1(cre)Svs>/Gata4<+>,Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln

http://metadb.riken.jp/0013006I129S1Sv129X1SvJFVBNGata4tm1creSvsGata4TgSox3GFPTyrHolNplnTgSox3GFPTyrHolNplnGata4tm1creSvsGata4TgSox3GFPTyrHolNpln

abnormal enteric neural crest cell migration_Gata4<tm1(cre)Svs>/Gata4<+>,Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion Hol, Nicolas Pilon
  http://metadb.riken.jp/db/mgi_rdf/MGI:5774445
• GATA binding protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:95664

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gata4<tm1(cre)Svs>/Gata4<+>,Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gata4<tm1(cre)Svs>|Gata4<+>|Tg(Sox3-GFP,Tyr)HolNpln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enteric neural crest cell migration
  http://purl.obolibrary.org/obo/MP_0013006

文献

http://purl.org/net/cito/citesAsAuthority

• Rodolphe. Soret, et.al., A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease., The Journal of clinical investigation, 2015, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/26571399