abnormal hindlimb bud morphology_Isl1<tm2Sev>/Isl1<tm2.1Sev>,Tg(Hoxb6-cre)#Mku/0

http://metadb.riken.jp/0013167I129S1Sv129X1SvJFVBNIsl1tm2SevIsl1tm21SevTgHoxb6creMku0TgHoxb6creMkuIsl1tm2SevIsl1tm21Sev

abnormal hindlimb bud morphology_Isl1<tm2Sev>/Isl1<tm2.1Sev>,Tg(Hoxb6-cre)#Mku/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Michael R Kuehn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4366042
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Isl1<tm2Sev>/Isl1<tm2.1Sev>,Tg(Hoxb6-cre)#Mku/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Hoxb6-cre)#Mku|Isl1<tm2Sev>|Isl1<tm2.1Sev>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hindlimb bud morphology
  http://purl.obolibrary.org/obo/MP_0013167

文献

http://purl.org/net/cito/citesAsAuthority

• Junji. Itou, et.al., Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22438573