embryonic lethality prior to tooth bud stage_Cyld<tm1Scs>/Cyld<tm1Scs>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

http://metadb.riken.jp/0013293I129S1Sv129X1SvJC57BL6NCyldtm1ScsCyldtm1ScsRipk3tm2VmdRipk3tm2VmdCyldtm1ScsRipk3tm2Vmd

embryonic lethality prior to tooth bud stage_Cyld<tm1Scs>/Cyld<tm1Scs>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• receptor-interacting serine-threonine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2154952
• CYLD lysine 63 deubiquitinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921506

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyld<tm1Scs>/Cyld<tm1Scs>,Ripk3<tm2Vmd>/Ripk3<tm2Vmd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyld<tm1Scs>|Ripk3<tm2Vmd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• embryonic lethality prior to tooth bud stage
  http://purl.obolibrary.org/obo/MP_0013293

文献

http://purl.org/net/cito/citesAsAuthority

• Kim. Newton, et.al., Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis., Science (New York, N.Y.), 2014, 343
  http://rdf.ncbi.nlm.nih.gov/pubmed/24557836